Endocrine Abstracts

Endocrine disruptors are chemicals that can alter functions of the endocrine system by several ways. Their risk assessment with regard to REACH legislation remains a challenge. In the present study, we propose an integrative evaluation for the effects of some endocrine disruptors on hormonal balance in male and female adult rats. We focused our work on the last step of steroidogenesis, where two enzymes are implicated: aromatase, which plays a central role by catalyzing the ir...